Other names: Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
CAS Number: 31362-50-2 check
Chemical formula: C71H110N24O18S
Molar mass: 1619.85
Bombesin/蛙皮素/铃蟾肽,是一种14个氨基酸的肽。最初由研究者从欧洲火腹蟾蜍(B. bombina)的皮肤中分离出来,并以其来源命名。它在哺乳动物中有两种已知的同源物,称为神经调节素B(neuromedin B)和胃泌素释放肽(gastrin-releasing peptide)。
铃蟾肽能够刺激G细胞释放胃泌素。它激活三种不同的G蛋白偶联受体,即BBR1、BBR2和BBR3。It also activates these receptors in the brain. Together with cholecystokinin, it is the second major source of negative feedback signals that stop eating behaviour.